Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526803 | 0.83 | HTT (0.71) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL10790188 | 0.81 | HTT (0.68) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL358355 | 0.81 | HTT (0.63) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL3164500 | 0.81 | ALDH1A1 (0.66) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL1060190 | 0.80 | KMT2A (0.49) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL1060188 | 0.80 | KMT2A (0.49) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL9693477 | 0.80 | HTT (0.58) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL9937593 | 0.79 | HTT (0.66) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL8980342 | 0.79 | HTT (0.61) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL4271625 | 0.79 | HTT (0.61) | HTTSMN1; SMN2MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |