SCHEMBL29952684

SCHEMBL29952684

Cc1ccc(B(O)O)c(OC(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.39
ACHE P22303 1/20 0.36
CYP2C9 P11712 2/20 0.35
KCNK3 O14649 2/20 0.35
KCNK9 Q9NPC2 2/20 0.35
CA2 P00918 1/20 0.34
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34
ENPP2 Q13822 1/20 0.34
PDE2A O00408 1/20 0.33
MRGPRX1 Q96LB2 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
SYK P43405 1/20 0.33
TTR P02766 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C8 P10632 1/20 0.33
CHRM1 P11229 1/20 0.33
TSHR P16473 1/20 0.33
ADRA1A P35348 1/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14237419 0.85 GPR3 (0.39) GPR3ACHEKCNK3KCNK9CA2
SCHEMBL3139123 0.81 GPR3 (0.42) GPR3CYP2C9PDE2ASMN1; SMN2CYP1A2
SCHEMBL29952484 0.81 MAOB (0.38) CYP2C9ENPP2PDE2AEPHX2ALDH1A1
SCHEMBL28952418 0.81 PDE2A (0.40) GPR3KCNK3KCNK9ENPP2PDE2A
SCHEMBL22684147 0.81 MAOB (0.38) CYP2C9ENPP2PDE2AEPHX2ALDH1A1
SCHEMBL25368443 0.80 MGLL (0.42) CYP2C9PDE2ACYP1A2ALDH1A1L3MBTL1
SCHEMBL31408917 0.80 PDE2A (0.36) ENPP2PDE2ATSHREPHX2ALDH1A1
SCHEMBL12004570 0.80 MAOA (0.40) CA2ENPP2SMN1; SMN2TSHRTDP1
SCHEMBL30214860 0.80 MAOA (0.40) CA2ENPP2SMN1; SMN2TSHRTDP1
SCHEMBL29951618 0.80 CNR2 (0.42) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed