Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707192 | 0.75 | GRM1 (0.34) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL30199232 | 0.75 | GRM1 (0.34) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL22575141 | 0.74 | GRM1 (0.34) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL20731174 | 0.74 | ACHE (0.38) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL25768687 | 0.74 | GRM1 (0.34) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL11926935 | 0.74 | ACHE (0.35) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL9877020 | 0.74 | ACHE (0.41) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL21606986 | 0.74 | ALK (0.34) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL18183641 | 0.73 | GRM1 (0.40) | GRM1ACHETP53CYP3A4MAPK1 | |
| SCHEMBL22691605 | 0.72 | MAP4K1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |