Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31096388 | 0.86 | SLC22A6 (0.51) | TDP1MAPTCA1CA2SLC22A6 | |
| SCHEMBL8389971 | 0.83 | MAPT (0.62) | TDP1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL8735765 | 0.81 | CA1 (0.55) | TDP1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL419245 | 0.80 | TDP1 (0.56) | TDP1MAPTCA1CA2SELL | |
| SCHEMBL12683255 | 0.78 | TDP1 (0.70) | TDP1MAPTCA1CA2SELL | |
| SCHEMBL17740051 | 0.77 | SELL (0.50) | TDP1MAPTCA1CA2SLC22A6 | |
| SCHEMBL7939012 | 0.77 | CA1 (0.59) | TDP1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL31746160 | 0.77 | TDP1 (0.53) | TDP1MAPTCA1CA2SELL | |
| SCHEMBL3936411 | 0.77 | ERN1 (0.51) | TDP1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL2059405 | 0.77 | TDP1 (0.53) | TDP1MAPTCA1CA2SELL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |