SCHEMBL419245

SCHEMBL419245

COc1c(O)ccc(C(=O)O)c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
MAPT P10636 1/20 0.56
SELL P14151 1/20 0.48
SELP P16109 1/20 0.48
HTT P42858 1/20 0.44
CSNK2A1 P68400 1/20 0.44
TPMT P51580 4/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
POLB P06746 1/20 0.43
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA2 P00918 2/20 0.42
CA14 Q9ULX7 2/20 0.42
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505827 0.89 TDP1 (0.61) TDP1MAPTHTTALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL2202243 0.87 TDP1 (0.59) TDP1MAPTHTTALDH1A1HSD17B10
SCHEMBL1438720 0.86 TDP1 (0.59) TDP1MAPTSELLSELPHTT
SCHEMBL12683255 0.86 TDP1 (0.70) TDP1MAPTSELLSELPHTT
SCHEMBL2059405 0.84 TDP1 (0.53) TDP1MAPTSELLSELPHTT
SCHEMBL6474772 0.84 TDP1 (0.58) TDP1MAPTSELLSELPHTT
SCHEMBL31746160 0.84 TDP1 (0.53) TDP1MAPTSELLSELPHTT
SCHEMBL3258548 0.83 ALDH1A1 (0.53) TDP1MAPTHTTALDH1A1HSD17B10
SCHEMBL11407285 0.83 MAPT (0.45) TDP1MAPTSELLSELPHTT
SCHEMBL6924772 0.82 TDP1 (0.51) TDP1MAPTSELLSELPHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11220650-B2 Grease composition SHELL OIL COMPANY (US) 2022-01-11 US claimed
US-11198830-B2 Grease composition SHELL OIL COMPANY (US) 2021-12-14 US claimed
CN-109316475-A Syringic acid/3,5- dimethoxy-4 '-hydroxybenzoic acid promotes the application in neural restoration drug in preparation 中国人民解放军第二军医大学第二附属医院 2019-02-12 CN claimed
EP-2448913-B1 CONTINUOUS METHOD FOR ACYLATING AMINO GROUP-CARRYING ORGANIC ACIDS CLARIANT FINANCE BVI LTD (VG) 2013-04-24 EP claimed
EP-2448904-B1 CONTINUOUS METHOD FOR PRODUCING ESTERS OF AROMATIC CARBOXYLIC ACIDS CLARIANT FINANCE BVI LTD (VG) 2013-04-17 EP claimed
CN-102898630-A Copolyarylate and its preparation method SHANGHAI GENIUS ADVANCED MAT 2013-01-30 CN claimed
CN-102816381-A Raw material for preparing container bag TONGLING TIANRUN PACKAGING CO LTD 2012-12-12 CN claimed
CN-102389412-B Eye drops for treating cataract UNIV GUANGZHOU CHINESE MEDICINE 2012-11-21 CN claimed
EP-2470632-A1 IMPROVED WASHING PERFORMANCE USING RADICAL TRAPS Henkel AG & Co. KGaA (DE) 2012-07-04 EP claimed
US-20120157370-A1 WASHING PERFORMANCE USING RADICAL TRAPS HENKEL AG & CO. KGAA (DE) 2012-06-21 US claimed
US-20120090983-A1 Continuous Method For Acylating Amino Group-Carrying Organic Acids CLARIANT FINANCE (BVI) LIMITED (VG) 2012-04-19 US claimed
US-20120088918-A1 Continuous Method For Producing Esters Of Aromatic Carboxylic Acids CLARIANT FINANCE (BVI) LIMITED (VG) 2012-04-12 US claimed
CN-102389412-A Eye drops for treating cataract UNIV GUANGZHOU CHINESE MEDICINE 2012-03-28 CN claimed
WO-2011023716-A1 IMPROVED WASHING PERFORMANCE USING RADICAL TRAPS HENKEL AG & CO. KGAA (DE) 2011-03-03 WO claimed
JP-2007502314-A 2007-02-08 JP claimed
EP-1633190-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.p.A. (IT) 2006-03-15 EP claimed
WO-2004103074-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.P.A. (IT) 2004-12-02 WO claimed
EP-4680706-A1 BIODEGRADABLE GREASE COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2026-01-21 EP disclosed
EP-0874843-A1 NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES HOECHST MARION ROUSSEL, INC. (US) 1998-11-04 EP disclosed
WO-1997022604-A1 NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES HOECHST MARION ROUSSEL, INC. (US) 1997-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157370-A1 WASHING PERFORMANCE USING RADICAL TRAPS MPO, DNASE1, PLD4 TDP1 201/4885MAPT 2017/4885SELL 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.