Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 10/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923461 | 0.88 | ERN1 (0.53) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL7939012 | 0.86 | CA1 (0.59) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL31562444 | 0.86 | CA1 (0.46) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL3936411 | 0.86 | ERN1 (0.51) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL10920936 | 0.84 | ALDH1A1 (0.46) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL5250735 | 0.84 | ERN1 (0.59) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL31035587 | 0.84 | ERN1 (0.54) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL29952736 | 0.81 | TDP1 (0.49) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL10923398 | 0.81 | FDPS (0.44) | CA1CA2ALDH1A1LCKGLA | |
| SCHEMBL28577429 | 0.79 | CA1 (0.47) | CA1CA2ALDH1A1LCKGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847379-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5677342-A | ANTIDIABETIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1997008126-A1 | PHENOXY ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS AND ANTIHYPERGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |