SCHEMBL12683255

SCHEMBL12683255

COc1c(O)ccc(C(=O)O)c1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.70
MAPT P10636 2/20 0.70
SELL P14151 1/20 0.57
SELP P16109 1/20 0.57
HTT P42858 2/20 0.43
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
CSNK2A1 P68400 1/20 0.42
TPMT P51580 4/20 0.42
POLB P06746 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PDE4A P27815 1/20 0.41
BLVRB P30043 1/20 0.41
KDR P35968 1/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758178 0.86 MAPT (0.52) TDP1MAPTSELLSELPHTT
SCHEMBL419245 0.86 TDP1 (0.56) TDP1MAPTSELLSELPHTT
SCHEMBL10082308 0.85 KMT2A (0.55) TDP1MAPTHTTALDH1A1HSD17B10
SCHEMBL1438720 0.84 TDP1 (0.59) TDP1MAPTSELLSELPHTT
SCHEMBL23120369 0.84 ALDH1A1 (0.52) TDP1MAPTHTTALDH1A1HSD17B10
SCHEMBL2059405 0.82 TDP1 (0.53) TDP1MAPTSELLSELPHTT
SCHEMBL6474772 0.82 TDP1 (0.58) TDP1MAPTSELLSELPHTT
2-Hydroxy-3,4-Dimethoxybenzoic Acid SCHEMBL419244 0.82 MAPT (1.00) TDP1MAPTSELLSELPHTT
SCHEMBL31746160 0.82 TDP1 (0.53) TDP1MAPTSELLSELPHTT
SCHEMBL17371291 0.82 TDP1 (0.68) TDP1MAPTSELLSELPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1912581-A Measuring method of ammonia concentration and ammonia diagnostic reagent kit WANG ERZHONG (CN) 2007-02-14 CN claimed
WO-2017051020-A1 DYE COMPOSITION COMPRISING A RESORCINOL-BASED COUPLER AND AN OXIDATION BASE L'OREAL (FR) 2017-03-30 WO disclosed
EP-2710432-A1 TONER Canon Kabushiki Kaisha (JP) 2014-03-26 EP disclosed
EP-2710430-A1 TONER Canon Kabushiki Kaisha (JP) 2014-03-26 EP disclosed
WO-2013035885-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 WO disclosed
WO-2012157780-A1 TONER CANON KABUSHIKI KAISHA (JP) 2012-11-22 WO disclosed
WO-2012157781-A1 TONER CANON KABUSHIKI KAISHA (JP) 2012-11-22 WO disclosed
WO-2012101058-A1 4-TOLYL-ETHYNYL-OCTAHYDRO-INDOLE-1-ESTER DERIVATIVES NOVARTIS AG (CH) 2012-08-02 WO disclosed
CN-1912581-A Measuring method of ammonia concentration and ammonia diagnostic reagent kit WANG ERZHONG (CN) 2007-02-14 CN disclosed