Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16195782 | 0.88 | ALDH1A1 (0.54) | CA1CA2CA9ALDH1A1HTT | |
| SCHEMBL29956502 | 0.88 | ALDH1A1 (0.54) | CA1CA2CA9ALDH1A1HTT | |
| SCHEMBL29953706 | 0.79 | LMNA (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2905511 | 0.79 | LMNA (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7926321 | 0.78 | CA12 (0.62) | CA12CA1CA2CA9HTR2C | |
| SCHEMBL16600609 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAA | |
| SCHEMBL29958209 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAA | |
| SCHEMBL1369061 | 0.75 | CA12 (0.54) | CA12CA1CA2CA9HTR2C | |
| SCHEMBL17049845 | 0.73 | KMT2A (0.65) | CA12CA1CA2CA9HTR2C | |
| SCHEMBL634316 | 0.73 | ALDH1A1 (0.71) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |