Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346453 | 0.98 | TSHR (0.56) | TSHRGGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL29956245 | 0.93 | TSHR (0.52) | TSHRGGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL15865588 | 0.89 | TSHR (0.70) | TSHRGGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL4906959 | 0.83 | — | — | |
| SCHEMBL29169584 | 0.83 | ALDH1A1 (0.42) | TSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL12429496 | 0.80 | TSHR (0.56) | TSHRGGPS1S1PR2S1PR1S1PR3 | |
| SCHEMBL8853018 | 0.80 | CA12 (0.42) | TSHRALDH1A1 | |
| SCHEMBL16790931 | 0.80 | DNM1 (0.61) | TSHRGGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL516480 | 0.80 | DNM1 (0.61) | TSHRGGPS1FDPSAGTR1OPRM1 | |
| Formic Acid SCHEMBL28426676 | 0.79 | S1PR2 (0.59) | GGPS1FDPSAGTR1OPRM1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |