Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.38 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285228 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7375093 | 0.79 | TSHR (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13159632 | 0.79 | CYP1A2 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4966189 | 0.78 | KDM4E (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29953053 | 0.78 | KDM4E (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4236738 | 0.78 | ENPP2 (0.37) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1821215 | 0.78 | KDM4E (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL132727 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EGAAENPP2 | |
| SCHEMBL29438369 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EGAAENPP2 | |
| SCHEMBL29957062 | 0.75 | ENPP2 (0.57) | ALDH1A1MAPTKMT2AKDM4EENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |