Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966189 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL186269 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL7375093 | 0.78 | TSHR (0.40) | KDM4EALDH1A1ENPP2L3MBTL1MEN1 | |
| SCHEMBL13159632 | 0.78 | CYP1A2 (0.47) | KDM4EALDH1A1ENPP2MEN1KMT2A | |
| SCHEMBL29952797 | 0.78 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL18836658 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL29957667 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL3038859 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL4236738 | 0.76 | ENPP2 (0.37) | KDM4EALDH1A1ENPP2L3MBTL1MEN1 | |
| SCHEMBL29991689 | 0.76 | TRPV4 (0.33) | KDM4EALDH1A1HPGDHSD17B10ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |