Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955073 | 0.85 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL29954695 | 0.85 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL29956665 | 0.80 | CA1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL29954966 | 0.78 | HPGD (0.48) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9272857 | 0.77 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL12330474 | 0.75 | CA1 (0.43) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9270577 | 0.74 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL257984 | 0.72 | CA1 (0.67) | RAB9AMAPTALDH1A1CA1CA2 | |
| SCHEMBL10404144 | 0.72 | ALDH1A1 (0.54) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9274347 | 0.72 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |