Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274483 | 0.86 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL9270577 | 0.82 | NPC1 (0.49) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL9262825 | 0.79 | NPC1 (0.40) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL10789684 | 0.75 | LTA4H (0.44) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL256693 | 0.74 | EHMT2 (0.48) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL9265556 | 0.73 | MAPT (0.41) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL9268024 | 0.72 | NR1I2 (0.49) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9856294 | 0.72 | PPARG (0.39) | SMN1; SMN2ALDH1A1ALOX5PPARGPPARA | |
| SCHEMBL9856269 | 0.72 | TAAR1 (0.44) | SMN1; SMN2CYP1A2CYP2D6CYP19A1ALOX5 | |
| SCHEMBL9268482 | 0.72 | PPARG (0.42) | ALOX5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389651-A | Nitrogen-containing heterocyclyl-oxy and -thio compounds useful as pesticides | SANDOZ LTD. (CH) | 1995-02-14 | — | — | US | disclosed |