Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140749 | 1.00 | PDK2 (0.41) | PDK2ALDH1A1KMT2AFFAR4PARP10 | |
| SCHEMBL29653552 | 0.81 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL41862 | 0.81 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL5663433 | 0.80 | AR (0.31) | PPARGPPARA | |
| SCHEMBL28079449 | 0.80 | RXRA (0.44) | PDK2ALDH1A1KMT2AFFAR4PARP10 | |
| SCHEMBL3719192 | 0.79 | ALDH1A1 (0.43) | PDK2ALDH1A1KMT2AFFAR4PARP10 | |
| SCHEMBL29636290 | 0.77 | ALDH1A1 (0.44) | PDK2ALDH1A1KMT2AFFAR4PARP10 | |
| SCHEMBL20659060 | 0.77 | ALDH1A1 (0.44) | PDK2ALDH1A1KMT2AFFAR4PARP10 | |
| SCHEMBL12896068 | 0.77 | SLC6A4 (0.43) | PDK2ALDH1A1KMT2AFFAR4PARP10 | |
| SCHEMBL14198838 | 0.77 | PDK2 (0.41) | PDK2ALDH1A1KMT2AFFAR4PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |