Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079310 | 0.88 | RXRA (0.47) | RXRARXRBRXRGFFAR4PDK2 | |
| SCHEMBL3140749 | 0.80 | PDK2 (0.41) | RXRARXRBRXRGFFAR4PDK2 | |
| SCHEMBL29952840 | 0.80 | PDK2 (0.41) | RXRARXRBRXRGFFAR4PDK2 | |
| SCHEMBL5953481 | 0.79 | L3MBTL1 (0.43) | RXRARXRBRXRGPDK2ALDH1A1 | |
| SCHEMBL3140756 | 0.78 | RXRA (0.43) | RXRARXRBRXRGFFAR4PDK2 | |
| SCHEMBL7587408 | 0.76 | AR (0.41) | ALDH1A1S1PR1AR | |
| SCHEMBL3719192 | 0.76 | ALDH1A1 (0.43) | RXRARXRBRXRGFFAR4PDK2 | |
| SCHEMBL27821346 | 0.74 | RXRA (0.48) | RXRARXRBRXRGARCTSS | |
| SCHEMBL12896068 | 0.74 | SLC6A4 (0.43) | RXRARXRBRXRGFFAR4PDK2 | |
| SCHEMBL14198838 | 0.74 | PDK2 (0.41) | RXRARXRBRXRGFFAR4PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104144927-B | S1p receptor modulators | 明治制果药业株式会社 | 2016-08-24 | — | — | CN | disclosed |