Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555121 | 0.89 | HPGD (0.33) | EPHX1GAACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL15333259 | 0.89 | SIGMAR1 (0.33) | EPHX1GAACYP2C19CYP2C9HTT | |
| SCHEMBL15330465 | 0.88 | SIGMAR1 (0.33) | KMT2ASMN1; SMN2MEN1KDM4EL3MBTL1 | |
| SCHEMBL29955496 | 0.83 | SIGMAR1 (0.36) | EPHX1GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL15329588 | 0.82 | XIAP (0.33) | ALDH1A1KDM4EMMP1MMP2MMP3 | |
| SCHEMBL2559507 | 0.81 | SIGMAR1 (0.40) | EPHX1ALDH1A1KDM4ELMNA | |
| SCHEMBL29956844 | 0.80 | KDM4E (0.45) | EPHX1HTTALDH1A1KDM4EEPHX2 | |
| SCHEMBL29956239 | 0.80 | KDM4E (0.48) | EPHX1HTTALDH1A1KMT2AKDM4E | |
| SCHEMBL29952973 | 0.79 | SIGMAR1 (0.33) | ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL2555745 | 0.79 | KDM4E (0.31) | GAAHTTKDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |