Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956844 | 0.97 | KDM4E (0.45) | KDM4EALDH1A1CASP6SIGMAR1TSHR | |
| SCHEMBL15330465 | 0.85 | SIGMAR1 (0.33) | KDM4ESIGMAR1KMT2A | |
| SCHEMBL15329588 | 0.85 | XIAP (0.33) | KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL29955496 | 0.82 | SIGMAR1 (0.36) | KDM4EALDH1A1SIGMAR1EPHX1KMT2A | |
| SCHEMBL29952973 | 0.81 | SIGMAR1 (0.33) | KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL2557932 | 0.81 | EPHX1 (0.41) | SIGMAR1HTTEPHX1KMT2A | |
| SCHEMBL2555745 | 0.81 | KDM4E (0.31) | KDM4ESIGMAR1HTTEPHX2 | |
| SCHEMBL2559507 | 0.80 | SIGMAR1 (0.40) | KDM4EALDH1A1SIGMAR1TSHREPHX1 | |
| SCHEMBL29952848 | 0.80 | EPHX1 (0.42) | KDM4EALDH1A1HTTEPHX2EPHX1 | |
| SCHEMBL15333259 | 0.80 | SIGMAR1 (0.33) | KDM4ESIGMAR1HTTEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |