Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554079 | 0.88 | POLB (0.38) | SIGMAR1ALDH1A1KDM4EFKBP1A | |
| SCHEMBL15330465 | 0.84 | SIGMAR1 (0.33) | SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL15329588 | 0.84 | XIAP (0.33) | SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL29955496 | 0.81 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL29956239 | 0.81 | KDM4E (0.48) | SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL29956844 | 0.81 | KDM4E (0.45) | SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL2557932 | 0.80 | EPHX1 (0.41) | SIGMAR1 | |
| SCHEMBL2555745 | 0.80 | KDM4E (0.31) | SIGMAR1KDM4E | |
| SCHEMBL2559507 | 0.79 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1LMNAKDM4E | |
| SCHEMBL29952848 | 0.79 | EPHX1 (0.42) | ALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |