Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956731 | 0.81 | HTT (0.41) | DAOMEN1KMT2AALDH1A1HTT | |
| SCHEMBL3756416 | 0.81 | IDO1 (0.52) | TSHRPNMTTAAR1MEN1MAPT | |
| SCHEMBL29955728 | 0.76 | CYP3A4 (0.42) | PNMTMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL29953131 | 0.76 | KDM4E (0.44) | TSHRALDH1A1NPSR1KDM4ECYP1A2 | |
| SCHEMBL318499 | 0.76 | KDM4E (0.44) | TSHRALDH1A1NPSR1KDM4ECYP1A2 | |
| SCHEMBL23850015 | 0.75 | TAAR1 (0.47) | PIK3CADAOHDAC3HDAC1HDAC2 | |
| SCHEMBL1503218 | 0.74 | PIK3CA (0.45) | PIK3CADAOTSHRHDAC3HDAC1 | |
| SCHEMBL16388285 | 0.74 | PIK3CA (0.45) | PIK3CADAOTSHRHDAC3HDAC1 | |
| SCHEMBL3538182 | 0.73 | IDO1 (0.46) | TAAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5650950 | 0.72 | PIK3CA (0.47) | PIK3CADAOTSHRHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |