Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028871 | 0.78 | HRH3 (0.41) | IDO1TAAR1LMNAAGXTMAOB | |
| SCHEMBL5672968 | 0.76 | IDO1 (0.48) | IDO1TAAR1LMNAAGXTMAOB | |
| SCHEMBL2560685 | 0.75 | TAAR1 (0.50) | IDO1TAAR1LMNACYP2A6AGXT | |
| SCHEMBL12374395 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAOB | |
| SCHEMBL855864 | 0.74 | TP53 (0.43) | IDO1TAAR1LMNACYP2A6ALDH1A1 | |
| SCHEMBL11740256 | 0.74 | ESR1 (0.50) | IDO1TAAR1LMNASLC6A2MEN1 | |
| SCHEMBL4890253 | 0.74 | IDO1 (0.46) | IDO1TAAR1LMNACYP2A6AGXT | |
| SCHEMBL3890376 | 0.74 | TAAR1 (0.42) | IDO1TAAR1CYP2A6HTR2AKDM4E | |
| SCHEMBL29952853 | 0.73 | PIK3CA (0.41) | IDO1TAAR1SLC6A4SLC6A3MEN1 | |
| SCHEMBL3756416 | 0.73 | IDO1 (0.52) | IDO1TAAR1LMNASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983068-B1 | NOVEL ARGINASE INHIBITORS | UNIV GRONINGEN (NL) | 2024-03-20 | — | — | EP | disclosed |
| US-11845767-B2 | Arginase inhibitors | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-12-19 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20220227791-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2022-07-21 | — | — | US | disclosed |
| EP-3983068-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2022-04-20 | — | — | EP | disclosed |
| CN-113444090-A | Compound and application thereof | 北京鼎材科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020249821-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-12-17 | — | — | WO | disclosed |
| EP-2086960-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-03-05 | — | — | EP | disclosed |
| US-20100173930-A1 | Certain Chemical Entities, Compositions and Methods | CYTOKINETICS, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7741354-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2010-06-22 | — | — | US | disclosed |
| WO-2000075202-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000075203-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| EP-0947561-A1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5739155-A | Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0549866-B1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID CO (US) | 1997-08-13 | — | — | EP | disclosed |
| US-5484807-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | BASF AKTIENGESELLSCHAFT | 1996-01-16 | — | — | US | disclosed |
| US-5468877-A | FOR PROTECTING CROPS | AMERICAN CYANAMID COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
| US-5306827-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5284863-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0549866-A1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227791-A1 | NOVEL ARGINASE INHIBITORS | ARG1, ARG2, ARGLU1 | IDO1 34/4885TAAR1 683/4885LMNA 4660/4885 |
| US-11845767-B2 | Arginase inhibitors | ARG1, ARG2, ARGLU1 | IDO1 29/4885TAAR1 769/4885LMNA 4591/4885 |
| US-20100173930-A1 | Certain Chemical Entities, Compositions and Methods | TNNC1, TNNI3, TNNT2 | IDO1 3291/4885TAAR1 2537/4885LMNA 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.