SCHEMBL29952899

SCHEMBL29952899

CNS(=O)(=O)c1cccc(B(O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.49
TNNI3K Q59H18 5/20 0.46
EGFR P00533 2/20 0.46
LMNA P02545 2/20 0.44
PTBP1 P26599 1/20 0.44
ENPP2 Q13822 4/20 0.44
GAA P10253 2/20 0.43
MEN1 O00255 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
TSHR P16473 1/20 0.43
MAPT P10636 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL521508 1.00 L3MBTL1 (0.49) L3MBTL1TNNI3KEGFRLMNAPTBP1
SCHEMBL2242660 0.82 L3MBTL1 (0.61) L3MBTL1TNNI3KEGFRLMNAPTBP1
SCHEMBL934547 0.81 KMT2A (0.47) LMNAMEN1KMT2ATSHRMAPT
SCHEMBL532021 0.81 HTR2B (0.47) LMNAENPP2ALDH1A1SMN1; SMN2CA2
SCHEMBL520205 0.81 MAPT (0.65) LMNAENPP2MEN1RAB9AKMT2A
SCHEMBL361979 0.79 ENPP2 (0.61) L3MBTL1LMNAENPP2GAAMEN1
SCHEMBL6096 0.79 ENPP2 (0.61) ENPP2GAAKDM4EALDH1A1SMN1; SMN2
SCHEMBL15655705 0.77 GAA (0.49) L3MBTL1LMNAGAAKMT2AALDH1A1
SCHEMBL4945399 0.77 L3MBTL1 (0.52) L3MBTL1TNNI3KEGFRLMNAPTBP1
SCHEMBL8205185 0.77 KMT2A (0.56) L3MBTL1TNNI3KEGFRLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339145-A Bicyclic fused ring derivatives or salts thereof and pharmaceutical compositions containing the same 柳韩洋行 2024-07-12 CN disclosed
CN-113840820-B Phthalazinone compounds and uses thereof ST制药株式会社 2024-05-03 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed