SCHEMBL6096

SCHEMBL6096

CS(=O)(=O)c1cccc(B(O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 7/20 0.61
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
MGLL Q99685 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
GAA P10253 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953072 0.89 MGLL (0.58) ENPP2ALDH1A1KDM4EMGLL
SCHEMBL31538443 0.81 TSHR (0.55) ENPP2ALDH1A1KDM4EMGLLSMN1; SMN2
SCHEMBL30904969 0.81 ENPP2 (0.50) ENPP2ALDH1A1KDM4EMGLLCA4
SCHEMBL521495 0.80 PSIP1 (0.52) ENPP2ALDH1A1KDM4EMGLLCA4
SCHEMBL522374 0.80 ENPP2 (0.43) ENPP2ALDH1A1SMN1; SMN2GAAHSD17B10
SCHEMBL10051059 0.79 CA1 (0.55) ENPP2ALDH1A1SMN1; SMN2GAAHSD17B10
SCHEMBL29955889 0.79 CA2 (0.64) ENPP2ALDH1A1KDM4EMGLLCA4
SCHEMBL585145 0.79 CA2 (0.64) ENPP2ALDH1A1KDM4EMGLLCA4
SCHEMBL957571 0.79 RAB9A (0.51) ENPP2ALDH1A1KDM4EMGLLSMN1; SMN2
SCHEMBL17442195 0.79 ENPP2 (0.44) ENPP2ALDH1A1KDM4EMGLLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107674098-B Aryl-containing boronic acids99mTc complex, its medicine box formula and application 中国医学科学院阜外医院 2021-12-07 CN claimed
EP-4743081-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP disclosed
US-20260085073-A1 PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS INC (US) 2026-03-26 US disclosed
EP-4705291-A1 IKK-ALPHA INHIBITORS Cancer Research Technology Limited (GB) 2026-03-11 EP disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 EP disclosed
EP-4667458-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG Kanaph Therapeutics Inc. (KR) 2025-12-24 EP disclosed
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed
US-20250352550-A1 SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE UNIV MASARYKOVA (CZ) 2025-11-20 US disclosed
US-20050043347-A1 Thienopyridine and furopyridine kinase inhibitors ABBVIE INC. 2005-02-24 US disclosed
WO-2005010009-A1 THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS ABBOTT LABORATORIES (US) 2005-02-03 WO disclosed
US-20050014753-A1 Novel compounds and compositions as protein kinase inhibitors IRM LLC (BM) 2005-01-20 US disclosed
WO-2004100947-A2 NOVEL CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2004-11-25 WO disclosed
US-6821980-B1 Substituted 5-benzyl-2,4-diaminopyrimidines BASILEA PHARMACEUTICA AG (CH) 2004-11-23 US disclosed
WO-2004089286-A2 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS IRM LLC (BM) 2004-10-21 WO disclosed
WO-2004084813-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2004-10-07 WO disclosed
US-20040192743-A1 Substituted azole derivatives as therapeutic agents TRANSTECH PHARMA, INC. 2004-09-30 US disclosed
WO-2004071447-A2 SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS TRANSTECH PHARMA INC. (US) 2004-08-26 WO disclosed
WO-2004009086-A1 SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP ELI LILLY AND COMPANY (US) 2004-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192743-A1 Substituted azole derivatives as therapeutic agents PTPRS, PTPRO, PTPRJ ENPP2 216/4885ALDH1A1 710/4885KDM4E 672/4885
US-20250352550-A1 SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE FLT3, ROS1, MAP4K2 ENPP2 1040/4885ALDH1A1 2094/4885KDM4E 814/4885
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 ENPP2 3353/4885ALDH1A1 700/4885KDM4E 684/4885
US-20050014753-A1 Novel compounds and compositions as protein kinase inhibitors ABL1, BCR, PDGFRA ENPP2 1760/4885ALDH1A1 3062/4885KDM4E 1310/4885
US-20050043347-A1 Thienopyridine and furopyridine kinase inhibitors ABL1, ERBB2, LCK ENPP2 2330/4885ALDH1A1 1899/4885KDM4E 1041/4885
US-20260085073-A1 PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY MALT1, BCL6, BCL3 ENPP2 1705/4885ALDH1A1 2586/4885KDM4E 2636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.