Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | GPR3 | P46089 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956393 | 0.82 | TUBB4A (0.46) | GPR3FFAR4ABL1 | |
| SCHEMBL320667 | 0.82 | TUBB4A (0.46) | GPR3FFAR4ABL1 | |
| SCHEMBL16955239 | 0.79 | PPARD (0.41) | GRM7KCNK3KCNK9TACR1PDE2A | |
| SCHEMBL29951073 | 0.78 | L3MBTL1 (0.44) | GRM7TACR1PDE2AGPR3FFAR4 | |
| SCHEMBL12847220 | 0.78 | MGLL (0.40) | PDE2AALDH1A1RXRARXRBRXRG | |
| SCHEMBL29952234 | 0.78 | MGLL (0.40) | PDE2AALDH1A1RXRARXRBRXRG | |
| SCHEMBL7691095 | 0.78 | APP (0.43) | GRM7KCNK3KCNK9TACR1PDE2A | |
| SCHEMBL8160442 | 0.78 | GRM7 (0.40) | GRM7KCNK3KCNK9TACR1PDE2A | |
| SCHEMBL16955235 | 0.78 | TACR1 (0.39) | GRM7KCNK3KCNK9TACR1PDE2A | |
| SCHEMBL4939627 | 0.77 | ALDH1A3 (0.41) | GRM7KCNK3KCNK9TACR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |