Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226511 | 0.81 | MAPT (1.00) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL2230037 | 0.77 | MAPT (0.62) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL645169 | 0.77 | MAPT (0.55) | MAPTNPSR1KDM4EALDH1A1GAA | |
| SCHEMBL21287698 | 0.77 | MAPT (0.55) | MAPTNPSR1KDM4EALDH1A1GAA | |
| SCHEMBL7011270 | 0.77 | MAPT (0.62) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL2227626 | 0.75 | ALDH1A1 (0.74) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL29957473 | 0.75 | ALDH1A1 (0.97) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL12442812 | 0.75 | MAPT (0.59) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL15329889 | 0.75 | MAPT (1.00) | MAPTNPSR1KDM4EALDH1A1HTT | |
| SCHEMBL2218011 | 0.74 | THRB (0.62) | MAPTNPSR1KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |