SCHEMBL29952972

SCHEMBL29952972

O=C(O)CNCC1CCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
CYP2D6 P10635 1/20 0.42
EPHX1 P07099 4/20 0.42
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 3/20 0.39
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8165369 0.95 CYP2D6 (0.47) ADH1BADH1CADH1AADH4ADH7
SCHEMBL157039 0.93 EPHX1 (0.50) ADH1BADH1CADH1AADH4ADH7
SCHEMBL524625 0.90
Hydrochloric Acid SCHEMBL30478821 0.88 TDP1 (0.44) ADH1BADH1CADH1AADH4ADH7
SCHEMBL22043849 0.82 TDP1 (0.40) CYP2D6EPHX1KDM4EKMT2AALDH1A1
SCHEMBL8991907 0.82 TDP1 (0.40) CYP2D6EPHX1KDM4EKMT2AALDH1A1
SCHEMBL24034733 0.80 SAT1 (0.39) CYP2D6KDM4EKMT2AALDH1A1MEN1
SCHEMBL8991891 0.80 TDP1 (0.39) CYP2D6EPHX1KDM4EKMT2AALDH1A1
SCHEMBL1808210 0.80 GABRA5 (0.53) EPHX1EPHX2
SCHEMBL31688784 0.80 EPHX1 (0.42) EPHX1KDM4EKMT2AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265718-A Radiolabeled compounds and uses thereof 国立大学法人大阪大学 2024-06-28 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed