⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30478821 | 0.97 | TDP1 (0.44) | — | |
| SCHEMBL8991907 | 0.91 | TDP1 (0.40) | — | |
| SCHEMBL22043849 | 0.91 | TDP1 (0.40) | — | |
| SCHEMBL8165369 | 0.90 | CYP2D6 (0.47) | — | |
| SCHEMBL29952972 | 0.90 | ADH1B (0.46) | — | |
| SCHEMBL24034733 | 0.89 | SAT1 (0.39) | — | |
| SCHEMBL20017737 | 0.89 | TDP1 (0.43) | — | |
| SCHEMBL8991891 | 0.89 | TDP1 (0.39) | — | |
| SCHEMBL157039 | 0.88 | EPHX1 (0.50) | — | |
| SCHEMBL1808210 | 0.84 | GABRA5 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4805909-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | claimed |
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | claimed |
| WO-2025034944-A9 | METHODS AND COMPOSITIONS FOR PROLONGED RENALASE AGONIST ACTIVITY | YALE UNIVERSITY (US) | 2025-03-13 | — | — | WO | disclosed |
| WO-2025034944-A1 | METHODS AND COMPOSITIONS FOR PROLONGED RENALASE AGONIST ACTIVITY | YALE UNIVERSITY (US) | 2025-02-13 | — | — | WO | disclosed |
| CN-116157140-A | Stable peptides with renal enzymatic agent activity | 贝索制药有限责任公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4157307-A2 | STABLE PEPTIDES HAVING RENALASE AGONIST ACTIVITY | Bessor Pharma, LLC (US) | 2023-04-05 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-2970243-A2 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144100-A2 | SGC STIMULATORS | NAKAI TAKASHI (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20130109581-A1 | POSITIVELY CHARGED SPECIES AS BINDING REAGENTS IN THE SEPARATION OF PROTEIN AGGREGATES FROM MONOMERS | NOVARTIS AG (CH) | 2013-05-02 | — | — | US | disclosed |
| US-4322339-A | Pharmacologically active peptides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| US-4283329-A | ANALGESICS | ELI LILLY AND COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| US-4283330-A | ANALGESICS | ELI LILLY AND COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0030845-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| EP-0030847-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| EP-0030846-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4265808-A | ANALGESICS | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4251439-A | ENKEPHALIN ANALOGS AS ANALGESICS | ELI LILLY AND COMPANY (US) | 1981-02-17 | — | — | US | disclosed |