Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524625 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL30478821 | 0.89 | TDP1 (0.44) | TDP1EPHX1CYP2D6ALDH1A1HPGD | |
| SCHEMBL22043849 | 0.83 | TDP1 (0.40) | TDP1EPHX1MEN1KMT2ACYP2D6 | |
| SCHEMBL8165369 | 0.82 | CYP2D6 (0.47) | EPHX1MEN1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL29952972 | 0.82 | ADH1B (0.46) | TDP1EPHX1MEN1KMT2ACYP2D6 | |
| SCHEMBL24034733 | 0.81 | SAT1 (0.39) | TDP1MEN1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL20017737 | 0.81 | TDP1 (0.43) | TDP1CYP2D6ALDH1A1HPGDPLG | |
| SCHEMBL8991891 | 0.81 | TDP1 (0.39) | TDP1EPHX1MEN1KMT2ACYP2D6 | |
| SCHEMBL157039 | 0.80 | EPHX1 (0.50) | EPHX1MEN1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL1808210 | 0.77 | GABRA5 (0.53) | EPHX1SLC6A1GABRA5GABRB2SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527882-A | BRADYKININ | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-06-18 | — | — | US | disclosed |