Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103025 | 1.00 | ERN1 (0.50) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9417632 | 0.86 | ERN1 (0.57) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL214270 | 0.83 | ALDH1A1 (0.44) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL16952733 | 0.83 | ALDH1A1 (0.39) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL16950618 | 0.83 | MEN1 (0.45) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL31023003 | 0.83 | ALDH1A1 (0.39) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL240574 | 0.81 | TDP1 (0.52) | ALDH1A1TDP1LMNAMAPTNPC1 | |
| SCHEMBL2841960 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL196088 | 0.78 | ERN1 (0.65) | ERN1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL27985682 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387951-A1 | PALLADIUM FREE PROCESSES FOR PREPARATION OF ACRYLATE COMPOUNDS | Amgen Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2023023201-A1 | PALLADIUM FREE PROCESSES FOR PREPARATION OF ACRYLATE COMPOUNDS | AMGEN INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |