Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417632 | 0.87 | ERN1 (0.57) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL5211004 | 0.82 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL196088 | 0.80 | ERN1 (0.65) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2841960 | 0.80 | ERN1 (0.50) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL27935920 | 0.80 | ERN1 (0.65) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL722136 | 0.78 | ALDH1A1 (0.67) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL29954426 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2366617 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2625726 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2422942 | 0.78 | GPR35 (0.58) | ERN1ALDH1A1TDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482221-B | bicyclic and tricyclic compounds as KATII inhibitors | PFIZER INC. (US) | 2014-10-22 | — | — | CN | disclosed |