Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417632 | 0.87 | ERN1 (0.57) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL196088 | 0.80 | ERN1 (0.65) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL27985682 | 0.80 | ERN1 (0.50) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL27935920 | 0.80 | ERN1 (0.65) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL103025 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL29952992 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2625726 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2422942 | 0.78 | GPR35 (0.58) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL29954426 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2366617 | 0.78 | ERN1 (0.49) | ERN1ALDH1A1TDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337675-A1 | ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Universidad De Chile (CL) | 2024-03-20 | — | — | EP | disclosed |
| EP-2267020-A2 | Binding polypeptides for B lymphocyte stimulator protein (BLyS) | Human Genome Sciences, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-2267017-A2 | Binding polypeptides for B lymphocyte stimulator protein (BLyS) | Human Genome Sciences, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| US-7608681-B2 | Methods and compositions for prolonging elimination half-times of bioactive compounds | GENENTECH, INC. (US) | 2009-10-27 | — | — | US | disclosed |
| EP-1674477-A2 | Binding polypeptides for B lymphocyte stimulator protein (BLYS) | Dyax Corp. (US) | 2006-06-28 | — | — | EP | disclosed |
| US-20040253247-A1 | Methods and compositions for prolonging elimination half-times of bioactive compounds | GENENTECH, INC. | 2004-12-16 | — | — | US | disclosed |
| US-4772684-A | HYPOTENSIVE OR HYPERTENSIVE | TRITON BIOSCIENCES, INC. (US) | 1988-09-20 | — | — | US | disclosed |