Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953152 | 0.91 | TP53 (0.41) | ELANETP53ALOX15LTA4HPLA2G2A | |
| SCHEMBL3790617 | 0.89 | LTA4H (0.41) | ELANELTA4HPTGS1PTGS2KMT2A | |
| SCHEMBL12982504 | 0.85 | NQO1 (0.38) | TP53ALOX15LTA4HKMT2AENPP2 | |
| SCHEMBL29953751 | 0.82 | ENPP2 (0.46) | LTA4HKMT2AENPP2MEN1ALDH1A1 | |
| SCHEMBL3785254 | 0.81 | TSHR (0.39) | ELANETP53LTA4HKMT2AENPP2 | |
| SCHEMBL16687415 | 0.81 | MAPT (0.36) | ELANELTA4HPTGS1PTGS2KMT2A | |
| SCHEMBL29778385 | 0.81 | MAPT (0.43) | ELANETP53LTA4HPTGS1PTGS2 | |
| SCHEMBL14489702 | 0.80 | ELANE (0.49) | ELANETP53ALOX15LTA4HPTGS1 | |
| SCHEMBL9123683 | 0.80 | ELANE (0.49) | ELANETP53ALOX15LTA4HPTGS1 | |
| SCHEMBL3786397 | 0.79 | PLA2G2A (0.47) | TP53LTA4HPLA2G2ACA2LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |