Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558651 | 0.85 | MAPT (0.46) | LMNAMAPTHPGDMAPK1HSD17B10 | |
| SCHEMBL2558238 | 0.82 | ALDH1A1 (0.48) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL17236440 | 0.81 | LIPE (0.51) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL10028470 | 0.81 | MAPT (0.58) | LMNAMAPTHPGDMAPK1HSD17B10 | |
| SCHEMBL2554884 | 0.80 | ENPP2 (0.59) | LMNAMAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2560524 | 0.80 | ENPP2 (0.52) | MAPTHPGDMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL2561404 | 0.80 | MRGPRX4 (0.51) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL16210297 | 0.77 | MRGPRX4 (0.53) | LMNAMAPTGAAHTTALDH1A1 | |
| SCHEMBL2558164 | 0.77 | KMT2A (0.47) | MAPTMAPK1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL2553915 | 0.74 | GLRA1 (0.46) | LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |