Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25660312 | 1.00 | ALOX5 (0.47) | ALOX5HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL29957197 | 1.00 | ALOX5 (0.47) | ALOX5HSD17B10TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4373252 | 0.82 | ALOX5 (0.50) | ALOX5SLC1A3SLC1A2SLC1A1HCAR2 | |
| SCHEMBL8882558 | 0.79 | ALOX5 (0.44) | ALOX5HSD17B10TDP1KMT2ASLC6A2 | |
| SCHEMBL19494055 | 0.78 | SRC (0.50) | ALOX5KMT2ACYP2D6SLC1A3SLC1A2 | |
| SCHEMBL7071590 | 0.77 | ALOX5 (0.46) | ALOX5TDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL10171590 | 0.77 | LMNA (0.52) | ALOX5KMT2ACYP2D6SLC1A3SLC1A2 | |
| Oxalic Acid SCHEMBL7019451 | 0.76 | ALOX5 (0.53) | ALOX5MEN1KMT2ASLC6A4SLC1A3 | |
| Oxalic Acid SCHEMBL7019455 | 0.76 | ALOX5 (0.53) | ALOX5MEN1KMT2ASLC6A4SLC1A3 | |
| SCHEMBL1219534 | 0.75 | ALOX5 (0.51) | ALOX5HSD17B10CYP2C9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |