Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953314 | 0.85 | ALDH1A1 (0.63) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL29957848 | 0.84 | GAA (0.53) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL29951078 | 0.82 | ALDH1A1 (0.50) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL29951512 | 0.80 | ALDH1A1 (0.48) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL29951638 | 0.78 | GAA (0.46) | GAAALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL29955747 | 0.78 | GAA (0.56) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL2555212 | 0.72 | CYP2A6 (0.44) | GAAALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2559106 | 0.71 | MEN1 (0.45) | GAAALDH1A1HTTMEN1KMT2A | |
| SCHEMBL29956317 | 0.69 | ALDH1A1 (0.69) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL29955823 | 0.69 | ALDH1A1 (0.47) | GAAALDH1A1HTTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |