Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195999 | 1.00 | KEAP1 (0.55) | KEAP1GAAMAPK1NPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29952686 | 0.98 | KEAP1 (0.53) | KEAP1GAAMAPK1NPC1L3MBTL1 | |
| SCHEMBL16568999 | 0.98 | KEAP1 (0.59) | KEAP1GAAMAPK1NPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29953158 | 0.96 | KEAP1 (0.57) | KEAP1GAAMAPK1NPC1L3MBTL1 | |
| SCHEMBL4008990 | 0.83 | ADRA2C (0.63) | MAPK1L3MBTL1MAPTADRA2CALDH1A1 | |
| SCHEMBL19533 | 0.82 | HSD17B10 (0.49) | GAANPC1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL27204343 | 0.82 | ADRB1 (0.61) | MAPTALDH1A1 | |
| SCHEMBL29953074 | 0.82 | HSD17B10 (0.49) | GAANPC1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL30899881 | 0.79 | KDM4E (0.47) | GAAMAPTADRA2CALDH1A1PKM | |
| SCHEMBL26219177 | 0.78 | MAPK1 (0.70) | KEAP1GAAMAPK1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |