Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955998 | 0.96 | RAB9A (0.46) | RAB9AMAPTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL29954455 | 0.86 | TSHR (0.48) | RAB9ATSHRNPC1TDP1HPGD | |
| SCHEMBL12180345 | 0.85 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL29957952 | 0.82 | BRD4 (0.47) | MAPTTSHRPOLBNPSR1ALDH1A1 | |
| SCHEMBL29951542 | 0.82 | TSHR (0.45) | RAB9ASMN1; SMN2TSHRNPC1TDP1 | |
| SCHEMBL2035552 | 0.81 | RAB9A (0.49) | RAB9AMAPTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL12180342 | 0.81 | PDE10A (0.51) | RAB9AMAPTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL29953902 | 0.79 | PTGDR2 (0.41) | RAB9ANPC1LMNAHPGD | |
| SCHEMBL1341685 | 0.78 | RAB9A (0.48) | RAB9AMAPTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL29950875 | 0.78 | HRH3 (0.48) | RAB9ASMN1; SMN2NPC1ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |