Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950875 | 0.96 | HRH3 (0.48) | BRD4HRH3ALDH1A1LIPEGLA | |
| SCHEMBL29954455 | 0.84 | TSHR (0.48) | BRD4TSHR | |
| SCHEMBL29953399 | 0.82 | RAB9A (0.50) | BRD4ALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL1710088 | 0.82 | ALDH1A1 (0.68) | BRD4HRH3ALDH1A1GLAMAPT | |
| SCHEMBL11403648 | 0.81 | NPC1 (0.48) | BRD4HRH3ALDH1A1GLAMAPT | |
| SCHEMBL11490890 | 0.81 | ADRA2C (0.63) | BRD4HRH3ALDH1A1GLAMAPT | |
| SCHEMBL11399267 | 0.80 | ALDH1A1 (0.60) | BRD4HRH3ALDH1A1GLAMAPT | |
| SCHEMBL29951542 | 0.80 | TSHR (0.45) | HRH3TSHRPOLB | |
| SCHEMBL29955998 | 0.79 | RAB9A (0.46) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL2346726 | 0.78 | HPGD (0.46) | BRD4HRH3ALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |