Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714916 | 1.00 | ATM (0.63) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL81598 | 0.84 | CA12 (0.52) | TDP1L3MBTL1ALDH1A1MAPTRECQL | |
| SCHEMBL29352153 | 0.82 | ALDH1A1 (0.61) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL10048328 | 0.81 | ATM (0.63) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL135162 | 0.79 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL9324919 | 0.79 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL31267166 | 0.78 | ALDH1A1 (0.46) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL13389659 | 0.78 | ALDH1A1 (0.46) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL13019496 | 0.77 | RAB9A (0.60) | ATMTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL13019493 | 0.77 | RAB9A (0.60) | ATMTDP1L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |