Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019496 | 0.94 | RAB9A (0.60) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL13019493 | 0.94 | RAB9A (0.60) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL12714916 | 0.82 | ATM (0.63) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL29953400 | 0.82 | ATM (0.63) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL314267 | 0.81 | ALDH1A1 (0.93) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL9066312 | 0.81 | ALDH1A1 (0.93) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL8141436 | 0.79 | TSHR (0.60) | ALDH1A1SRD5A2CES2CES1TP53 | |
| SCHEMBL761393 | 0.79 | CES2 (0.48) | ALDH1A1L3MBTL1ATMRAB9ALMNA | |
| SCHEMBL111501 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL6061130 | 0.78 | ALDH1A1 (1.00) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956232-B | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-09-16 | — | — | CN | claimed |
| CN-114014838-A | Compound and preparation method and application thereof | 山东师范大学 | 2022-02-08 | — | — | CN | claimed |
| CN-113956232-A | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-01-21 | — | — | CN | claimed |
| CN-114014838-B | Compound and preparation method and application thereof | 山东师范大学 | 2024-03-19 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-113956232-B | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-114014838-A | Compound and preparation method and application thereof | 山东师范大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113956232-A | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-01-21 | — | — | CN | disclosed |