Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15208759 | 1.00 | CYP19A1 (0.62) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL3791521 | 0.84 | PGR (0.81) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL14937571 | 0.80 | PGR (0.72) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL343776 | 0.80 | HTR6 (0.73) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL664321 | 0.79 | KMT2A (0.75) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL29561272 | 0.79 | PGR (0.67) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL15649873 | 0.78 | HSD17B2 (0.56) | CYP19A1ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL19336603 | 0.77 | GPR27 (0.67) | ALOX15GPR27PKMMEN1KMT2A | |
| SCHEMBL14434547 | 0.77 | MAPT (0.65) | CYP19A1PGRALOX15ALDH1A1TSHR | |
| SCHEMBL9305039 | 0.77 | CYP19A1 (0.67) | CYP19A1PGRALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |