Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956760 | 0.92 | BCHE (0.38) | ENPP2BCHELIPEALDH1A1KMT2A | |
| SCHEMBL14120573 | 0.87 | RORC (0.39) | ENPP2TTRMAPTKMT2ALMNA | |
| SCHEMBL29956843 | 0.82 | PTGS1 (0.32) | ALDH1A1LPLLIPG | |
| SCHEMBL29953456 | 0.80 | ENPP2 (0.40) | ENPP2TTRMAPTLMNACYP2C9 | |
| SCHEMBL1811195 | 0.80 | ENPP2 (0.40) | ENPP2TTRMAPTLMNACYP2C9 | |
| SCHEMBL29957240 | 0.79 | SCN9A (0.44) | CYP2C9 | |
| SCHEMBL366465 | 0.79 | SCN9A (0.44) | CYP2C9 | |
| SCHEMBL12037985 | 0.76 | SSTR4 (0.39) | CSNK2A1BCHELIPEMCOLN3MEN1 | |
| SCHEMBL29957127 | 0.75 | SMN1; SMN2 (0.37) | ENPP2CSNK2A1BCHELIPEMEN1 | |
| SCHEMBL16734291 | 0.75 | RORC (0.37) | ENPP2TTRLMNACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |