Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955589 | 1.00 | SIGMAR1 (0.59) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL29954761 | 0.99 | SIGMAR1 (0.57) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL29955492 | 0.94 | KDM4E (0.52) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2563652 | 0.88 | KDM4E (0.50) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2557931 | 0.88 | SIGMAR1 (0.46) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL29956236 | 0.86 | SIGMAR1 (0.54) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL29956969 | 0.84 | SIGMAR1 (0.63) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2557592 | 0.83 | L3MBTL1 (0.61) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL29950821 | 0.82 | SIGMAR1 (0.60) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2556252 | 0.81 | LMNA (0.47) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |