Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.67 |
| ▸ | CTSB | P07858 | 1/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.67 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.67 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.67 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 2/20 | 0.61 |
| ▸ | HNF4A | P41235 | 2/20 | 0.59 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28208328 | 0.85 | KLKB1 (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL28222381 | 0.85 | CFD (0.46) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL29182113 | 0.81 | KLKB1 (0.67) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL30929929 | 0.81 | KLKB1 (0.67) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL5484868 | 0.81 | HMGB1 (0.44) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL418713 | 0.81 | KLKB1 (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL7150326 | 0.81 | CA12 (0.59) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL29414416 | 0.80 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL10950033 | 0.80 | LCK (0.89) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL160646 | 0.80 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |