Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.43 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177931 | 0.87 | KDM4E (0.50) | HMGB1CXCL12KLKB1CTSBMMP9 | |
| SCHEMBL11009620 | 0.85 | NR1H4 (0.49) | HMGB1CXCL12CFDKLKB1CTSB | |
| SCHEMBL28222381 | 0.85 | CFD (0.46) | HMGB1CXCL12CFDKLKB1CTSB | |
| SCHEMBL6859574 | 0.82 | KLKB1 (0.62) | HMGB1CXCL12CFDKLKB1CTSB | |
| SCHEMBL29953483 | 0.81 | KLKB1 (0.67) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL13652492 | 0.81 | ALDH1A1 (0.50) | HMGB1CXCL12CFDKLKB1CTSB | |
| SCHEMBL5225010 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12CFDKLKB1CTSB | |
| SCHEMBL12900623 | 0.80 | LMNA (0.46) | ALDH1A1POLBMEN1KMT2ANR1H4 | |
| SCHEMBL19748200 | 0.79 | HMGB1 (0.46) | HMGB1CXCL12CFDKLKB1CTSB | |
| SCHEMBL11445335 | 0.79 | HMGB1 (0.46) | HMGB1CXCL12CFDKLKB1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116407584-A | A honeyed pill for strengthening waist and kidney and its quality detection method | 江西省芙蓉堂药业股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-110806459-A | Multi-medicine-flavor rapid thin-layer identification method and containing device for Erdi decoction reference substance | 东阿阿胶股份有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-106918674-B | It is a kind of treat soreness of waist and knee joint, sciatica Chinese medicine composition detection method | 广州白云山陈李济药厂有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-106918674-A | It is a kind of to treat soreness of waist and knee joint, the detection method of the Chinese medicine composition of sciatica | 广州白云山陈李济药厂有限公司 | 2017-07-04 | — | — | CN | claimed |
| CN-102359992-B | Bone-setting tablet, method thereof for identifying and measuring content | TONGHUA ZHENG HE PHARMACEUTICAL CO LTD | 2012-12-19 | — | — | CN | claimed |
| CN-102359992-A | Bone-setting tablet, method thereof for identifying and measuring content | TONGHUA ZHENG HE PHARMACEUTICAL CO LTD | 2012-02-22 | — | — | CN | claimed |
| CN-101293053-A | Novel preparation method for donkey-hide gelatin hematonic and quality control method | HENAN NEW SIFANG PHARMACEUTICA (CN) | 2008-10-29 | — | — | CN | claimed |
| CN-1321639-C | Arthritis therapeutic drug | SHANGHAI AMBROSIA PHARMACEUTIC (CN) | 2007-06-20 | — | — | CN | claimed |
| US-20070129426-A1 | Therapeutic drugs for arthritis | SHANGHAI AMBROSIA PHARMACEUTICAL CO., LTD. (CN) | 2007-06-07 | — | — | US | claimed |
| CN-1743843-A | 18-ingredient ginseng qi-tonifying ointment quality standard detecting method | SHANGHAI LEIYUNSHANG PHARMACEU (CN) | 2006-03-08 | — | — | CN | claimed |
| CN-1634037-A | Arthritis therapeutic drug | SHANGHAI AMBROSIA PHARMACEUTIC (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-118330122-A | Thin-layer detection method of cortex lycii radicis medicinal material or prescription granule and application of thin-layer detection method in counterfeit identification | 广东一方制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115308352-B | Quality control method of herba Aristolochiae Mollissimae sample | 江阴天江药业有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116407584-A | A honeyed pill for strengthening waist and kidney and its quality detection method | 江西省芙蓉堂药业股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-115308352-A | Quality control method of mollissima sample | 江阴天江药业有限公司 | 2022-11-08 | — | — | CN | disclosed |
| US-20070129426-A1 | Therapeutic drugs for arthritis | SHANGHAI AMBROSIA PHARMACEUTICAL CO., LTD. (CN) | 2007-06-07 | — | — | US | disclosed |
| CN-1810809-A | Coumarether compound and new use of its composition | SHANGHAI ANPU BIOLOG SCI TECH (CN) | 2006-08-02 | — | — | CN | disclosed |
| CN-1743843-A | 18-ingredient ginseng qi-tonifying ointment quality standard detecting method | SHANGHAI LEIYUNSHANG PHARMACEU (CN) | 2006-03-08 | — | — | CN | disclosed |
| CN-1634037-A | Arthritis therapeutic drug | SHANGHAI AMBROSIA PHARMACEUTIC (CN) | 2005-07-06 | — | — | CN | disclosed |
| US-5260335-A | Tetragalloylquinic acid derivatives, gallic acid and methyl gallate | PLANTAMED ARZNEIMITTEL GMBH (DE) | 1993-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129426-A1 | Therapeutic drugs for arthritis | SYVN1, CHIA, HCAR3 | HMGB1 2058/4885CXCL12 2366/4885CFD 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.