Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560065 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL29953636 | 0.84 | ALDH1A1 (0.66) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL825342 | 0.84 | ALDH1A1 (0.66) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL6914412 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL30206812 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL5805320 | 0.81 | ALDH1A1 (0.87) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL8372730 | 0.81 | ALDH1A1 (0.87) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL22160270 | 0.80 | FDPS (0.47) | ALDH1A1HPGDHTTSMN1; SMN2MAPT | |
| SCHEMBL30737431 | 0.80 | ALDH1A1 (0.66) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL21828406 | 0.79 | ALDH1A1 (0.83) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |