Sugi Predict

Sugi Predict / Compounds / SCHEMBL825342

SCHEMBL825342

SCHEMBL825342

C#CCOc1ccccc1C=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.66
▸ HPGD P15428 3/20 0.66
▸ HTT P42858 1/20 0.66
▸ SMN1; SMN2 Q16637 1/20 0.66
▸ PTGDR2 Q9Y5Y4 1/20 0.54
▸ CA12 O43570 1/20 0.49
▸ CA2 P00918 1/20 0.49
▸ CA9 Q16790 1/20 0.49
▸ KMT2A Q03164 4/20 0.47
▸ LMNA P02545 3/20 0.47
▸ GAA P10253 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ RECQL P46063 1/20 0.47
▸ MAPT P10636 2/20 0.45
▸ SRC P12931 1/20 0.44
▸ MAOB P27338 1/20 0.44
▸ TDP1 Q9NUW8 2/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953636 1.00 ALDH1A1 (0.66) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL30206812 0.86 ALDH1A1 (0.68) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL30737431 0.85 ALDH1A1 (0.66) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL29953484 0.84 ALDH1A1 (0.69) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4270827 0.83 ALDH1A1 (0.68) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL2857103 0.83 HPGD (0.44) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL29263864 0.83 HPGD (0.44) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL11350879 0.81 CA12 (0.49) ALDH1A1HPGDHTTSMN1; SMN2CA12
SCHEMBL5307057 0.81 ALDH1A1 (0.66) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4442714 0.80 CA2 (0.49) ALDH1A1HPGDHTTSMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213611-B Pyran [4,3-b ] pyridine-linked covalent organic framework material and synthesis method thereof 兰州大学 2023-09-29 — — CN claimed
CN-108840828-B 2- ((1-benzyl-1, 2, 3-triazole-4-yl) methoxyl) benzaldehyde compound and preparation method thereof 中国医科大学 2020-06-09 — — CN claimed
US-20250172566-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2025-05-29 — — US disclosed
EP-4469803-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2024-12-04 — — EP disclosed
US-20230339879-A1 SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS NORTHWESTERN UNIVERSITY 2023-10-26 — — US disclosed
CN-114213611-B Pyran [4,3-b ] pyridine-linked covalent organic framework material and synthesis method thereof 兰州大学 2023-09-29 — — CN disclosed
CN-114213611-B Pyran [4,3-b ] pyridine-linked covalent organic framework material and synthesis method thereof 兰州大学 2023-09-29 — — CN disclosed
WO-2023144545-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2023-08-03 — — WO disclosed
US-11639340-B2 Substituted chromanes, analogs thereof, and methods of use and synthesis NORTHWESTERN UNIVERSITY (US) 2023-05-02 — — US disclosed
US-11639340-B2 Substituted chromanes, analogs thereof, and methods of use and synthesis NORTHWESTERN UNIVERSITY (US) 2023-05-02 — — US disclosed
CN-112028955-B Trimethoxylated arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof 绍兴文理学院元培学院 2022-05-06 — — CN disclosed
WO-1999016746-A1 AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 1999-04-08 — — WO disclosed
US-4551467-A Vasodilating cyanoalkyl esters of 1,4-dihydropyridines BAYER AKTIENGESELLSCHAFT (DE) 1985-11-05 — — US disclosed
EP-0039863-A1 1,4-Dihydropyridines with different substituents in positions 2 and 6, processes for their preparation and their use in medicines BAYER AG (DE) 1981-11-18 — — EP disclosed
US-4248873-A Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1981-02-03 — — US disclosed
EP-0012180-A1 1,4-Dihydropyridine compounds, their preparation, pharmaceutical compositions containing said compounds and preparation of these compositions BAYER AG (DE) 1980-06-25 — — EP disclosed
US-4179500-A 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 — — US disclosed
EP-0002208-A1 Nitro 1,4-dihydropyridines, medicaments containing them and their manufacture BAYER AG (DE) 1979-06-13 — — EP disclosed
EP-0001769-A1 Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use BAYER AG (DE) 1979-05-16 — — EP disclosed
US-4109008-A SUBSTITUTED WITH AN AMIDINO AND A 1,3-DIMETHYL-2-OXO-BENZIMIDAZOL- 5-YL RADICAL HEXACHIMIE (FR) 1978-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639340-B2 Substituted chromanes, analogs thereof, and methods of use and synthesis TYR, ME1, PNPO ALDH1A1 444/4885HPGD 515/4885HTT 2777/4885
US-20230339879-A1 SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS TYR, ME1, PNPO ALDH1A1 444/4885HPGD 515/4885HTT 2777/4885
US-20250172566-A1 SACCHARIDE SENSING SYSTEMS GALE, SLC2A8, SLC2A4 ALDH1A1 3359/4885HPGD 3468/4885HTT 2584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.