Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724783 | 0.80 | LMNA (0.40) | LMNAKMT2A | |
| SCHEMBL1244717 | 0.80 | GABRP (0.44) | LMNAKMT2A | |
| SCHEMBL27911015 | 0.76 | KMT2A (0.43) | LMNAKMT2A | |
| SCHEMBL2723305 | 0.74 | APP (0.36) | LMNAKMT2A | |
| SCHEMBL24386890 | 0.73 | SSTR4 (0.32) | — | |
| SCHEMBL7224834 | 0.73 | KDM4E (0.40) | — | |
| SCHEMBL29102890 | 0.73 | SSTR4 (0.32) | — | |
| SCHEMBL27572185 | 0.72 | LOXL2 (0.39) | LMNAKMT2A | |
| SCHEMBL31197968 | 0.70 | PRKCI (0.32) | LMNA | |
| SCHEMBL613810 | 0.70 | MAPT (0.36) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |