Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936184 | 1.00 | MEN1 (0.37) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL29935609 | 0.86 | MEN1 (0.37) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL23536007 | 0.83 | MEN1 (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL29666971 | 0.83 | MEN1 (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL30777455 | 0.73 | BCL2L1 (0.45) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL1044992 | 0.73 | BCL2L1 (0.50) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL1616679 | 0.73 | BCL2L1 (0.45) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL25299513 | 0.72 | ERN1 (0.40) | TDP1ERN1 | |
| SCHEMBL19835774 | 0.72 | ADRA2A (0.47) | — | |
| SCHEMBL19249411 | 0.72 | BCL2L1 (0.48) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |