SCHEMBL1044992

SCHEMBL1044992

O=Cc1cccc2c1CCCC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.50
BAD Q92934 1/20 0.50
TSHR P16473 4/20 0.42
LMNA P02545 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
THRB P10828 2/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 7/20 0.40
THRA P10827 1/20 0.38
ERN1 O75460 1/20 0.38
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HTT P42858 2/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19249411 0.98 BCL2L1 (0.48) BCL2L1BADTSHRLMNAMEN1
SCHEMBL30777455 0.96 BCL2L1 (0.45) BCL2L1BADTSHRLMNAMEN1
SCHEMBL1616679 0.96 BCL2L1 (0.45) BCL2L1BADTSHRLMNAMEN1
Dimethylamine SCHEMBL6542151 0.93 BCL2L1 (0.44) BCL2L1BADTSHRLMNAMEN1
SCHEMBL3453076 0.83 BCL2L1 (0.43) BCL2L1BADTSHRLMNAMEN1
SCHEMBL3453685 0.80 ALDH1A1 (0.43) BCL2L1BADTSHRLMNAMEN1
SCHEMBL9136887 0.79 BCL2L1 (0.50) BCL2L1BADTSHRLMNAMEN1
SCHEMBL19729202 0.78 L3MBTL1 (0.39) BCL2L1BADTSHRLMNAMEN1
SCHEMBL231793 0.75 BCL2L1 (0.45) BCL2L1BADTSHRLMNAMEN1
SCHEMBL19729204 0.75 BCL2L1 (0.46) BCL2L1BADTSHRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130029990-A1 PYRAZOLE P38 MAP KINASE INHIBITORS RESPIVERT LTD. (GB) 2013-01-31 US claimed
EP-0511087-B1 Sweetening agents derived from l-glutamic acid; process for their preparation NOFRE CLAUDE (FR) 1995-06-28 EP claimed
JP-5123130-A None JP disclosed
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2026-05-07 US disclosed
EP-4710922-A2 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2026-03-18 EP disclosed
EP-4003337-B1 ARYL HYDROCARBON RECEPTOR ACTIVATORS UNIV OREGON STATE (US) 2026-03-11 EP disclosed
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS PBC (US) 2026-01-29 US disclosed
EP-4676999-A1 SULFUR-CONTAINING HETEROCYCLIC COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-01-14 EP disclosed
US-12473262-B2 Aryl hydrocarbon receptor activators OREGON STATE UNIVERSITY (US) 2025-11-18 US disclosed
EP-4626854-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2025-10-08 EP disclosed
US-20250270210-A1 BCL-2 Inhibitor BEIGENE, LTD. (KY) 2025-08-28 US disclosed
US-4301278-A BY HYDROGENATION IN THE PRESENCE OF A CATALYST CIBA-GEIGY CORPORATION (US) 1981-11-17 US disclosed
US-4293462-A Process for the manufacture of enol derivatives, and intermediates CIBA-GEIGY CORPORATION (US) 1981-10-06 US disclosed
US-4256739-A 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4255328-A CEPHALOSPORINS CIBA-GEIGY CORPORATION (US) 1981-03-10 US disclosed
EP-0012180-A1 1,4-Dihydropyridine compounds, their preparation, pharmaceutical compositions containing said compounds and preparation of these compositions BAYER AG (DE) 1980-06-25 EP disclosed
EP-0001769-A1 Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use BAYER AG (DE) 1979-05-16 EP disclosed
US-4147864-A Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds CIBA-GEIGY CORPORATION (US) 1979-04-03 US disclosed
US-4110533-A PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-3987116-A ETHYNYLARYL COMPOUNDS AND DERIVATIVES THEREOF WILLIAM H. RORER, INC. (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270210-A1 BCL-2 Inhibitor BCL2, BCL2A1, BCL2L1 BCL2L1 3/4885BAD 14/4885TSHR 4278/4885
US-20130029990-A1 PYRAZOLE P38 MAP KINASE INHIBITORS MAPK1, MAP3K1, MAPK3 BCL2L1 2317/4885BAD 1602/4885TSHR 1216/4885
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR1H2 BCL2L1 945/4885BAD 793/4885TSHR 13/4885
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES TAS2R42, TAS2R4, TAS2R41 BCL2L1 2159/4885BAD 3813/4885TSHR 2405/4885
US-12473262-B2 Aryl hydrocarbon receptor activators AHR, ARNT, NR0B1 BCL2L1 1419/4885BAD 299/4885TSHR 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.