SCHEMBL1616679

SCHEMBL1616679

O=Cc1cccc2c1CCC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.45
BAD Q92934 1/20 0.45
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
THRB P10828 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 5/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
ERN1 O75460 2/20 0.38
HCAR1 Q9BXC0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30777455 1.00 BCL2L1 (0.45) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL1044992 0.96 BCL2L1 (0.50) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL19249411 0.94 BCL2L1 (0.48) BCL2L1BADMEN1KMT2ALMNA
Dimethylamine SCHEMBL6542151 0.89 BCL2L1 (0.44) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL3453685 0.83 ALDH1A1 (0.43) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL3453076 0.80 BCL2L1 (0.43) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL231793 0.79 BCL2L1 (0.45) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL27726086 0.76 BCL2L1 (0.39) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL9136887 0.75 BCL2L1 (0.50) BCL2L1BADMEN1KMT2ALMNA
SCHEMBL11741399 0.75 CYP2A6 (0.46) MEN1KMT2ALMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110268538-A Hole mobile material and the photovoltaic devices for using the hole mobile material 埃尼股份公司 2019-09-20 CN claimed
CN-110235263-A Polymer photovoltaic cell and its preparation process with inverted structure 埃尼股份公司 2019-09-13 CN claimed
CN-104297373-B A kind of tsaoko and fingerprint discrimination method in one's early teens GUANGXI UNIVERSITY OF CHINESE MEDICINE (CN) 2016-04-06 CN claimed
CN-104297373-A Fingerprint chromatogram identification method of amomum tsaoko and alpinia katsumadai UNIV GUANGXI CHINESE MEDICINE 2015-01-21 CN claimed
US-3968163-A Preparation of 4 and 5-methylindanes MARION LABORATORIES, INC. (US) 1976-07-06 US claimed
EP-3880659-B1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2024-01-03 EP disclosed
CN-113272299-B Moisture-curable polyurethane compositions comprising oxazolidines SIKA技术股份公司 2023-07-07 CN disclosed
US-20230051589-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-02-16 US disclosed
US-20230051589-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-02-16 US disclosed
CN-110536880-B Process for producing indanecarbaldehyde 三菱瓦斯化学株式会社 2022-07-05 CN disclosed
EP-3898619-A1 MOISTURE-CURING POLYURETHANE COMPOSITION CONTAINING OXAZOLIDINE Sika Technology AG (CH) 2021-10-27 EP disclosed
EP-3880659-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY Novartis AG (CH) 2021-09-22 EP disclosed
EP-0518818-A2 Arylethers, their manufacture and use as medicament CIBA-GEIGY AG (CH) 1992-12-16 EP disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed
US-4071562-A 4,5-Dialkoxy-6 or 7-indanaldehydes MARION LABORATORIES, INC. (US) 1978-01-31 US disclosed
US-4071562-A 4,5-Dialkoxy-6 or 7-indanaldehydes MARION LABORATORIES, INC. (US) 1978-01-31 US disclosed
US-3968163-A Preparation of 4 and 5-methylindanes MARION LABORATORIES, INC. (US) 1976-07-06 US disclosed
US-3968163-A Preparation of 4 and 5-methylindanes MARION LABORATORIES, INC. (US) 1976-07-06 US disclosed
US-3963723-A HYPOTENSIVE MARION LABORATORIES, INC. (US) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230051589-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NLRP1, NLRP3, NOD1 BCL2L1 4249/4885BAD 4265/4885MEN1 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.